Inflammatory Oligodendrocyte Precursor Cells and Remyelination in MS

In this video, Peter Calabresi, MD, discusses the findings from his study, which suggested that inhibiting immune activation of oligodendrocyte precursor cells may foster remyelination among patients with multiple sclerosis. Read the transcript here. Dr Calabresi and his team will be presented with an award for this study at the American Neurological Association’s 145th Annual Meeting.

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Peter Calabresi, MD, is a professor of neurology, director of the Johns Hopkins Multiple Sclerosis Center, and director of the Divison of Neuroimmunology at Johns Hopkins University in Baltimore, Maryland.

Reference:
Kirby L, Jin J, Gonzalez Cardona J, et al. Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination. Nature Comm. 2020;10:3887. doi:10.1038/s41467-019-11638-3